Search results for " High flow nasal therapy"

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High flow nasal therapy versus noninvasive ventilation as initial ventilatory strategy in COPD exacerbation: a multicenter non-inferiority randomized…

2020

Abstract Background The efficacy and safety of high flow nasal therapy (HFNT) in patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease (AECOPD) are unclear. Our aim was to evaluate the short-term effect of HFNT versus NIV in patients with mild-to-moderate AECOPD, with the hypothesis that HFNT is non-inferior to NIV on CO2 clearance after 2 h of treatment. Methods We performed a multicenter, non-inferiority randomized trial comparing HFNT and noninvasive ventilation (NIV) in nine centers in Italy. Patients were eligible if presented with mild-to-moderate AECOPD (arterial pH 7.25–7.35, PaCO2 ≥ 55 mmHg before ventilator support). Primary endpoint was the mean di…

MaleExacerbationEquivalence Trials as TopicCritical Care and Intensive Care MedicineAcute respiratory failurelaw.invention03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineRandomized controlled triallawClinical endpointmedicineHumansCannulaAcute respiratory failure; Chronic obstructive pulmonary disease; High flow nasal cannula; High flow nasal therapy; Noninvasive ventilation030212 general & internal medicineHigh flow nasal therapyAgedCOPDbusiness.industryResearchhigh flow oxygen therapy high flow nasal cannula noninvasive ventilation COPD carbon dioxide acute respiratory failureChronic obstructive pulmonary diseaselcsh:Medical emergencies. Critical care. Intensive care. First aidOxygen Inhalation Therapylcsh:RC86-88.9Middle Agedmedicine.diseaseSymptom Flare UpConfidence intervalHigh flow nasal cannula030228 respiratory systemItalyAnesthesiaBreathingNoninvasive ventilationFemaleHigh flowbusinessNoninvasive ventilationHuman
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Effectiveness and safety of a new helmet CPAP configuration allowing tidal volume monitoring in patients with COVID-19.

2021

Abstract Background High generated tidal volumes (Vt) have been correlated with higher risk of self-induced lung injury and worse clinical outcome. This study aimed to evaluate the effectiveness and safety of a new helmet continuous positive airway pressure delivered (h-CPAP) configuration allowing Vt monitoring in patients affected by COVID-19. Methods This prospective observational study was performed in the respiratory intermediate care unit of University Hospital in Turin, Italy, between March 24th, and June 15th, 2020. Included patients were treated with CPAP via a single-limb intentional leak configuration by a turbine-driven ventilator, provided with a dedicated patch. Effectiveness …

Pulmonary and Respiratory MedicineLeakTidal volume monitoringmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)List of abbreviations: ARF Acute respiratory failuremedicine.medical_treatmentLung injuryTidal volumeVt Tidal volumeCPAPMedicineIn patientContinuous positive airway pressureTidal volumeHelmetCPAP Continuous positive airway pressureRICU Respiratory intermediate care unitbusiness.industryCOVID-19ICU Intensive care unitEmergency medicineHFNT High flow nasal therapyObservational studyOriginal ArticleTDVs turbine-driven ventilatorsbusinessPulmonology
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High flow nasal therapy in immunocompromised patients with acute respiratory failure: A systematic review and meta-analysis.

2019

Abstract Purpose The role of high-flow nasal therapy (HFNT) as compared to conventional oxygen therapy (COT) in immunocompromised patients admitted to intensive care unit (ICU) with acute respiratory failure (ARF) remains unclear. We conducted a systematic review and meta-analysis in order to address this issue. Methods We searched PubMed, Medline and Embase until November 7th, 2018. Randomized controlled trials (RCTs), non-randomized prospective and retrospective evidence were selected. Observational studies were considered for sensitivity analysis. Primary outcome was mortality rate; intubation rate was a secondary outcome. Results We included four studies in the primary analysis: one RCT…

medicine.medical_specialtyCritical CareAcute respiratory failure High flow nasal cannula High flow nasal therapy Immunocompromised patients Mechanical ventilation Noninvasive ventilation Oxygen therapy Cannula Humans Immunocompromised Host Intubation Intratracheal Noninvasive Ventilation Oxygen Inhalation Therapy Randomized Controlled Trials as Topic Respiratory Distress Syndrome Adult Critical Caremedicine.medical_treatmentAcute respiratory failureCritical Care and Intensive Care Medicinelaw.inventionImmunocompromised Host03 medical and health sciencesMechanical ventilation0302 clinical medicineRandomized controlled triallawInternal medicineOxygen therapyIntubation IntratrachealImmunocompromised patientmedicineCannulaHumansIntubationHigh flow nasal therapyRandomized Controlled Trials as TopicRespiratory Distress Syndromebusiness.industryMortality rateOxygen Inhalation Therapy030208 emergency & critical care medicineRetrospective cohort studyOdds ratioOxygen therapyIntensive care unitHigh flow nasal cannula030228 respiratory systemMeta-analysisbusinessNoninvasive ventilation
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